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Trial intelligence / Profile preview
Phase 2a umbrella study of frexalimab, brivekimig, and rilzabrutinib in primary FSGS or minimal change disease
2024-511775-15-00Phase 2Authorised
- Sponsor
- Sanofi
- Start
- Jan 2025
- Modality
- Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
- Countries
- 22
01
Overview
Phase 2, randomised, double-blind trial of frexalimab, brivekimig and rilzabrutinib in focal segmental glomerulosclerosis (FSGS) and nephrosis (4 arms), sponsored by Sanofi. Primary endpoint: Percent reduction in urine protein to creatinine ratio. Planned start Jan 2025; status: authorised.
02
Drugs
frexalimabbrivekimigrilzabrutinib
03
Conditions
focal segmental glomerulosclerosis (FSGS)nephrosis
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Study design, results and competitive context are available in the Gosset platform where reported.
Competitive context
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