Trial intelligence / Profile preview

Window-of-opportunity phase II trial of Olaparib ± Durvalumab before primary debulking surgery in high-grade epithelial ovarian cancer

2024-511780-28-00Phase 2Authorised

Sponsor
AGO Research
Start
Mar 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of olaparib and durvalumab in epithelial ovarian cancer (EOC), fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (2 arms), sponsored by AGO Research. Primary endpoint: Feasibility of window-of-opportunity procedure. Planned start Mar 2024; status: authorised.

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Drugs

olaparibdurvalumab
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Conditions

epithelial ovarian cancer (EOC)fallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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