Trial intelligence / Profile preview

ARROS-1: NVL-520 in Advanced ROS1-positive Solid Tumors

2024-511793-71-00Phase 2Authorised

Sponsor
Nuvalent
Start
Apr 2024
Modality
Small Molecules
Countries
14
01

Overview

Phase 2, open-label trial of zidesamtinib in non-small cell lung cancer (NSCLC) and solid neoplasms (2 arms), sponsored by Nuvalent. Primary endpoints: Phase 1: Recommended Phase 2 Dose (RP2D) and Maximum Tolerated Dose (MTD) and Phase 2: Objective Response Rate (ORR). Planned start Apr 2024; status: authorised.

02

Drugs

zidesamtinib
03

Conditions

non-small cell lung cancer (NSCLC)solid neoplasms

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