Trial intelligence / Profile preview

BAPTIST study of baricitinib in calcium pyrophosphate deposition disease

2024-511864-95-00Phase 2Authorised

Sponsor
IRCCS Ospedale Galeazzi-Sant'Ambrogio
Start
Sep 2024
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of baricitinib, methotrexate, hydroxychloroquine, colchicine and methylprednisolone in chondrocalcinosis (CPPD) (2 arms), sponsored by IRCCS Ospedale Galeazzi-Sant'Ambrogio. Primary endpoint: Change from baseline in CD68 at 12 weeks. Planned start Sep 2024; status: authorised.

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Drugs

baricitinibmethotrexatehydroxychloroquinecolchicinemethylprednisolone
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Conditions

chondrocalcinosis (CPPD)

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