Trial intelligence / Profile preview

AZD2811 + durvalumab maintenance in first-line ES-SCLC

2024-511887-10-00Phase 2Authorised

Sponsor
AstraZeneca
Start
Jul 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Nanoparticles → Drug Delivery Systems
Countries
3
01

Overview

Phase 2, open-label, single-arm trial of defosbarasertib and durvalumab in small cell lung cancer (SCLC), sponsored by AstraZeneca. Primary endpoint: Maintenance participants alive and progression free at 12 months (APF12). Planned start Jul 2024; status: authorised.

02

Drugs

defosbarasertibdurvalumab
03

Conditions

small cell lung cancer (SCLC)

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