Trial intelligence / Profile preview

LXH254 combination therapy in previously treated unresectable or metastatic BRAFV600 or NRAS mutant melanoma

2024-511934-11-00Phase 2Authorised

Sponsor
Novartis
Start
Jun 2024
Modality
Small Molecules
Countries
11
01

Overview

Phase 2, randomised, open-label trial of naporafenib in melanoma (5 arms), sponsored by Novartis. Primary endpoint: Confirmed objective response rate (ORR) per RECIST v1.1 (local assessment). Planned start Jun 2024; status: authorised.

02

Drugs

naporafenib
03

Conditions

melanoma

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Available in the Gosset platform where reported.

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