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STARBOARD: encorafenib + binimetinib + pembrolizumab vs placebo + pembrolizumab in BRAF V600E/K melanoma

2024-512038-13-00Phase 3Authorised

Sponsor
Pfizer
Start
Sep 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
22
01

Overview

Phase 3, randomised, double-blind trial in melanoma comparing encorafenib + binimetinib + pembrolizumab with placebo + pembrolizumab (2 arms). Primary endpoints: Safety lead-in: incidence of dose-limiting toxicities and Randomized Phase 3: objective response rate. Planned start Sep 2021; status: authorised.

02

Drugs

pembrolizumabencorafenibbinimetinib
03

Conditions

melanoma

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