Trial intelligence / Profile preview

SURPASS-3 in recurrent MAGE-A4-positive ovarian cancer

2024-512138-13-00Phase 2Completed

Sponsor
US WorldMeds
Start
Sep 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
5
01

Overview

Phase 2, randomised, open-label trial in ovarian cancer, primary peritoneal cancer (PPC) and fallopian tube cancer (PFTC) comparing ADP-A2M4CD8 monotherapy with ADP-A2M4CD8 plus Opdivo (2 arms). Primary endpoint: Objective response. Started Sep 2023; status: completed.

02

Drugs

ADP adoptive cell therapynivolumab
03

Conditions

ovarian cancerprimary peritoneal cancer (PPC)fallopian tube cancer (PFTC)

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