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Neoadjuvant Chemotherapy vs Chemotherapy plus Nivolumab ± BMS-986205 in Muscle-Invasive Bladder Cancer

2024-512158-12-00Phase 3Completed

Sponsor
Bristol Myers Squibb
Start
Jun 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
27
01

Overview

Phase 3, randomised trial of nivolumab and linrodostat in bladder cancer and muscle-invasive bladder cancer (MIBC) (3 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Pathological complete response (pCR) rate of neoadjuvant chemotherapy alone, Pathological complete response (pCR) rate of neoadjuvant nivolumab plus chemotherapy and 2 more. Started Jun 2024; status: completed.

02

Drugs

nivolumablinrodostat
03

Conditions

bladder cancermuscle-invasive bladder cancer (MIBC)

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