Trial intelligence / Profile preview

TROPION-Lung12

2024-512195-35-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Feb 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
23
01

Overview

Phase 3, randomised, open-label trial in Non-small cell lung cancer adenocarcinoma (NSCLC) comparing Datopotamab deruxtecan + rilvegostomig, Rilvegostomig monotherapy and Standard-of-care adjuvant therapy (3 arms). Primary endpoint: Disease-free survival (DFS). Planned start Feb 2025; status: authorised.

02

Drugs

datopotamab deruxtecanrilvegostomig
03

Conditions

Non-small cell lung cancer adenocarcinoma (NSCLC)

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