Trial intelligence / Profile preview

Methotrexate versus tocilizumab for giant cell arteritis

2024-512269-14-00Phase 3Completed

Sponsor
Centre Hospitalier Universitaire Dijon Bourgogne
Start
Jan 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in giant cell arteritis (GCA) comparing Tocilizumab arm with Methotrexate arm (2 arms). Primary endpoint: Sustained remission without prednisone schedule deviation at week 78. Started Jan 2020; status: completed.

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Drugs

tocilizumabmethotrexate
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Conditions

giant cell arteritis (GCA)

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