Trial intelligence / Profile preview

Bepirovirsen followed by HBV-targeted immunotherapy in chronic hepatitis B on nucleos(t)ide analogues

2024-512352-38-00Phase 2Completed

Sponsor
GSK
Start
May 2024
Modality
Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
15
01

Overview

Phase 2, randomised, single-blind trial of bepirovirsen and GSK3528869A in Chronic Hepatitis B (CHB) (2 arms), sponsored by GSK. Primary endpoints: Grade 3 adverse events, Serious adverse events and 3 more. Started May 2024; status: completed.

02

Drugs

bepirovirsenGSK3528869A
03

Conditions

Chronic Hepatitis B (CHB)

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