Trial intelligence / Profile preview

PelvEx II: Induction Chemotherapy Plus Chemoradiotherapy vs Chemoradiotherapy Alone in Locally Recurrent Rectal Cancer

2024-512526-28-00Phase 3Authorised

Sponsor
Catharina Ziekenhuis
Start
Apr 2024
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
5
01

Overview

Phase 3, randomised, open-label trial of capecitabine, irinotecan, fluorouracil, tegafur, folinic acid and 1 more in rectal cancer (2 arms), sponsored by Catharina Ziekenhuis. Primary endpoint: Rate of clear resection margins after surgery. Planned start Apr 2024; status: authorised.

02

Drugs

capecitabineirinotecanfluorouraciltegafurfolinic acid
03

Conditions

rectal cancer

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