Trial intelligence / Profile preview

TRIDENT-1 repotrectinib study in ROS1- or NTRK-rearranged advanced solid tumors

2024-512606-25-00Phase 2Authorised

Sponsor
Turning Point Therapeutics, Inc.
Start
Jul 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
18
01

Overview

Phase 2, open-label trial of repotrectinib in Nonhematologic neoplasms and non-small cell lung cancer (NSCLC) (6 arms), sponsored by Turning Point Therapeutics, Inc. Primary endpoint: Objective Response Rate. Planned start Jul 2024; status: authorised.

02

Drugs

repotrectinib
03

Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)

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