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Trial intelligence / Profile preview
Phase I/IIa first-in-human trial of BNT142 in CLDN6-positive advanced solid tumors
2024-512639-58-00Phase 2Completed
- Sponsor
- BioNTech SE
- Start
- Jul 2024
- Modality
- T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Vaccines & Immunotherapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
- Countries
- 6
01
Overview
Phase 2, open-label trial of BNT142 in Nonhematologic neoplasms, ovarian cancer, non-small cell lung cancer (NSCLC) and 3 more (2 arms), sponsored by BioNTech SE. Primary endpoints: Treatment-emergent adverse events, Dose reductions and discontinuations due to TEAEs and 2 more. Started Jul 2024; status: completed.
02
Drugs
BNT142
03
Conditions
Nonhematologic neoplasmsovarian cancernon-small cell lung cancer (NSCLC)endometrial cancer (EC)testicular cancer
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Competitive context
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