Trial intelligence / Profile preview

PLATO: glofitamab + pirtobrutinib in mantle cell lymphoma

2024-512922-27-00Phase 2Authorised

Sponsor
LMU Klinikum
Start
Nov 2025
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
5
01

Overview

Phase 2, open-label trial of glofitamab and pirtobrutinib in mantle cell lymphoma (MCL) (2 cohorts), sponsored by LMU Klinikum. Primary endpoint: Progression-free survival status at 24 months. Planned start Nov 2025; status: authorised.

02

Drugs

glofitamabpirtobrutinib
03

Conditions

mantle cell lymphoma (MCL)

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