Trial intelligence / Profile preview

ADELA: Elacestrant + Everolimus vs Elacestrant in ESR1-mutated ER+/HER2- Advanced Breast Cancer

2024-512926-27-00Phase 3Authorised

Sponsor
MEDSIR
Start
Nov 2024
Modality
Small Molecules, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
9
01

Overview

Phase 3, randomised, double-blind trial in breast cancer comparing Orserdu + everolimus with Orserdu + placebo (2 arms). Primary endpoint: Progression-free survival (PFS) by BIRC. Planned start Nov 2024; status: authorised.

02

Drugs

elacestranteverolimus
03

Conditions

breast cancer

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