Trial intelligence / Profile preview

HARMONi-3 first-line metastatic non-small cell lung cancer study

2024-513087-26-00Phase 3Authorised

Sponsor
Summit Therapeutics
Start
Sep 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
17
01

Overview

Phase 3, randomised, double-blind trial of ivonescimab, pembrolizumab, carboplatin, pemetrexed, paclitaxel and 1 more in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Summit Therapeutics. Primary endpoints: Overall survival and Progression-free survival by independent review. Planned start Sep 2024; status: authorised.

02

Drugs

ivonescimabpembrolizumabcarboplatinpemetrexedpaclitaxel
03

Conditions

non-small cell lung cancer (NSCLC)

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