Trial intelligence / Profile preview

FIBRAPLO haplo-identical transplantation in myelofibrosis

2024-513325-23-00Phase 2Authorised

Sponsor
Assistance publique - Hôpitaux de Paris
Start
Jul 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of treosulfan in myelofibrosis (MF), primary myelofibrosis (PMF) and post-polycythemia vera myelofibrosis (PPV-MF), sponsored by Assistance publique - Hôpitaux de Paris. Primary endpoint: Disease- and rejection-free survival at 12 months after HSCT. Planned start Jul 2024; status: authorised.

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Drugs

treosulfan
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Conditions

myelofibrosis (MF)primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)

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