Trial intelligence / Profile preview

Metro-PD1-1708

2024-513470-22-00Phase 2Completed

Sponsor
Centre Oscar Lambret
Start
Oct 2024
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of nivolumab, capecitabine, cyclophosphamide and vinblastine in Nonhematologic neoplasms, embryonal brain tumor, ependymoma and 4 more (3 arms), sponsored by Centre Oscar Lambret. Primary endpoints: Dose-limiting toxicity and Progression-free survival. Started Oct 2024; status: completed.

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Drugs

nivolumabcapecitabinecyclophosphamidevinblastine
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Conditions

Nonhematologic neoplasmsembryonal brain tumorependymomagliomarhabdomyosarcoma (RMS)

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