Trial intelligence / Profile preview

TWINS: Withdrawal of Moderate Efficacy Disease-Modifying Therapies in Inactive Relapsing-Remitting Multiple Sclerosis Patients Aged 55 and Over

2024-513475-41-00Phase 3Authorised

Sponsor
Strasbourg University Hospital
Start
Aug 2024
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, Small Molecules, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, open-label trial of interferon beta-1a, diroximel fumarate, dimethyl fumarate, interferon beta, teriflunomide and 1 more in multiple sclerosis (MS) (2 arms), sponsored by Strasbourg University Hospital. Primary endpoint: Time to first clinical and/or radiological disease activity. Planned start Aug 2024; status: authorised.

02

Drugs

interferon beta-1adiroximel fumaratedimethyl fumarateinterferon betateriflunomide
03

Conditions

multiple sclerosis (MS)

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