Trial intelligence / Profile preview

Randomized multifactorial primary prevention trial in high-risk subjects eligible for lung cancer CT screening

2024-513660-26-00Phase 2Authorised

Sponsor
Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano
Start
Aug 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of aspirin and cytisinicline in nicotine dependence and bronchial carcinoma (3 arms), sponsored by Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano. Primary endpoint: Reduction in elevated C-reactive protein after one year. Planned start Aug 2024; status: authorised.

02

Drugs

aspirincytisinicline
03

Conditions

nicotine dependencebronchial carcinoma

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