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Nivolumab + relatlimab fixed-dose combination with chemotherapy versus pembrolizumab with chemotherapy in first-line PD-L1-positive non-squamous metastatic or recurrent NSCLC

2024-513682-40-01Phase 3Authorised

Sponsor
Bristol Myers Squibb
Start
Jul 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
29
01

Overview

Phase 3, randomised, open-label trial of nivolumab, relatlimab, pembrolizumab, pemetrexed, carboplatin and 1 more in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Bristol Myers Squibb. Primary endpoint: Overall survival. Planned start Jul 2025; status: authorised.

02

Drugs

nivolumabrelatlimabpembrolizumabpemetrexedcarboplatin
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Conditions

non-small cell lung cancer (NSCLC)

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