Trial intelligence / Profile preview

MOIO reduced-intensity versus standard checkpoint immunotherapy maintenance trial

2024-513707-14-00Phase 3Authorised

Sponsor
Unicancer
Start
Jul 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of avelumab, dostarlimab, atezolizumab, cemiplimab, nivolumab and 2 more in bronchial carcinoma, renal cell carcinoma (RCC), head and neck cancer (HNC) and 15 more (2 arms), sponsored by Unicancer. Primary endpoint: Progression-free survival. Planned start Jul 2024; status: authorised.

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Drugs

avelumabdostarlimabatezolizumabcemiplimabnivolumab
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Conditions

bronchial carcinomarenal cell carcinoma (RCC)head and neck cancer (HNC)transitional cell carcinoma (TCC)triple-negative breast cancer (TNBC)

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Study design & results

Available in the Gosset platform where reported.

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Available in the Gosset platform where reported.

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