Trial intelligence / Profile preview

TACE-3 nivolumab plus TACE/TAE in intermediate-stage hepatocellular carcinoma

2024-513882-38-00Phase 3Authorised

Sponsor
The Clatterbridge Cancer Centre NHS Foundation Trust
Start
Oct 2022
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
2
01

Overview

Phase 3, randomised, open-label trial of nivolumab, mitomycin c, doxorubicin, cisplatin, epirubicin and 2 more in hepatocellular carcinoma (HCC) (2 arms), sponsored by The Clatterbridge Cancer Centre NHS Foundation Trust. Primary endpoints: Time to TACE/TAE progression and Overall survival. Planned start Oct 2022; status: authorised.

02

Drugs

nivolumabmitomycin cdoxorubicincisplatinepirubicin
03

Conditions

hepatocellular carcinoma (HCC)

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