Trial intelligence / Profile preview

Phase II PET Imaging of MMR-Expressing Macrophages in NSCLC Using 68GaNOTA-Anti-MMR VHH2

2024-514138-19-00Phase 2Authorised

Sponsor
UZ Brussel
Start
Oct 2024
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of 68Ga-UZBRU-VHH2 in non-small cell lung cancer (NSCLC), sponsored by UZ Brussel. Primary endpoint: Immunohistological MMR score on excised tissue. Planned start Oct 2024; status: authorised.

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Drugs

68Ga-UZBRU-VHH2
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Conditions

non-small cell lung cancer (NSCLC)

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