Trial intelligence / Profile preview

MagnetisMM-6 in transplant-ineligible newly diagnosed multiple myeloma

2024-514139-50-00Phase 3Authorised

Sponsor
Pfizer
Start
Nov 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
27
01

Overview

Phase 3, randomised, open-label trial in multiple myeloma (MM) comparing Elranatamab + daratumumab + lenalidomide with Daratumumab + bortezomib + lenalidomide + dexamethasone (2 arms). Primary endpoints: Dose-limiting toxicities, MRD-negative complete response rate at 12 months and 1 more. Planned start Nov 2022; status: authorised.

02

Drugs

elranatamabdaratumumablenalidomidebortezomibdexamethasone
03

Conditions

multiple myeloma (MM)

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