Trial intelligence / Profile preview

IMGN632 monotherapy in CD123-positive AML and other hematologic malignancies

2024-514195-40-00Phase 2Completed

Sponsor
AbbVie Inc.
Start
Feb 2019
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
4
01

Overview

Phase 2, open-label trial of pivekimab sunirine in acute myeloid leukemia (AML), Blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute lymphoblastic leukemia (ALL) and 4 more (7 arms), sponsored by AbbVie Inc. Primary endpoints: Maximum tolerated dose and recommended Phase 2 dose and Complete remission plus clinical complete remission. Started Feb 2019; status: completed.

02

Drugs

pivekimab sunirine
03

Conditions

acute myeloid leukemia (AML)Blastic plasmacytoid dendritic cell neoplasm (BPDCN)acute lymphoblastic leukemia (ALL)myelodysplastic syndrome (MDS)myeloproliferative disorder (MPD)

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