Trial intelligence / Profile preview

VICTORIA trial of valproic acid with anti-EGFR rechallenge in metastatic colorectal cancer

2024-514420-16-00Phase 2Authorised

Sponsor
Istituto Nazionale Tumori IRCCS Fondazione Pascale
Start
Dec 2024
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of valproic acid, panitumumab and irinotecan in colorectal adenocarcinoma and metastatic colorectal adenocarcinoma (mCRC) (2 arms), sponsored by Istituto Nazionale Tumori IRCCS Fondazione Pascale. Primary endpoints: Progression-free survival rate at 16 weeks and Progression-free survival rate at 8 weeks. Planned start Dec 2024; status: authorised.

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Drugs

valproic acidpanitumumabirinotecan
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Conditions

colorectal adenocarcinomametastatic colorectal adenocarcinoma (mCRC)

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