Trial intelligence / Profile preview

Phase 2 Study of AMG 193 in MTAP-deleted Advanced Non-Small Cell Lung Cancer

2024-514459-14-00Phase 2Authorised

Sponsor
Amgen
Start
Apr 2025
Modality
Small Molecules
Countries
25
01

Overview

Phase 2, single-arm trial of anvumetostat in non-small cell lung cancer (NSCLC), sponsored by Amgen. Primary endpoints: Objective response (OR) by RECIST 1.1 (primary), Incidence of treatment-emergent adverse events (TEAEs), grade ≥ 3 TEAEs, serious adverse events (SAEs), and events of interest (EOIs) (primary) and 2 more. Planned start Apr 2025; status: authorised.

02

Drugs

anvumetostat
03

Conditions

non-small cell lung cancer (NSCLC)

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