Trial intelligence / Profile preview

RIO trial of ART plus dual long-acting HIV broadly neutralizing antibodies versus ART plus placebo during analytical treatment interruption

2024-514564-13-00Phase 2Authorised

Sponsor
Imperial College London
Start
Jan 2025
Modality
Anti-infectious Disease mAbs → Neutralizing Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Naked Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
7
01

Overview

Phase 2, randomised trial of Teropavimab and zinlirvimab in human immunodeficiency virus infection (HIV) (2 arms), sponsored by Imperial College London. Primary endpoint: Time to viral rebound within 20 weeks after initial analytical treatment interruption. Planned start Jan 2025; status: authorised.

02

Drugs

Teropavimabzinlirvimab
03

Conditions

human immunodeficiency virus infection (HIV)

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