Trial intelligence / Profile preview

SURE-02 perioperative pembrolizumab + sacituzumab govitecan in muscle-invasive bladder cancer

2024-514569-20-00Phase 2Authorised

Sponsor
IRCCS Ospedale San Raffaele
Start
Oct 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pembrolizumab and sacituzumab govitecan in muscle-invasive bladder carcinoma (MIBC) and transitional cell carcinoma of the bladder (TCC), sponsored by IRCCS Ospedale San Raffaele. Primary endpoint: clinical complete response rate. Planned start Oct 2024; status: authorised.

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Drugs

pembrolizumabsacituzumab govitecan
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Conditions

muscle-invasive bladder carcinoma (MIBC)transitional cell carcinoma of the bladder (TCC)

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Study design & results

Available in the Gosset platform where reported.

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