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IMPROVE: Ibrutinib plus venetoclax with MRD-guided approach in relapsed/refractory CLL

2024-514686-19-00Phase 2Completed

Sponsor
IRCCS Ospedale San Raffaele
Start
Aug 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of venetoclax and ibrutinib in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), sponsored by IRCCS Ospedale San Raffaele. Primary endpoint: Minimal residual disease (MRD) negativity rate. Started Aug 2024; status: completed.

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Drugs

venetoclaxibrutinib
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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