Trial intelligence / Profile preview

Selinexor plus gemcitabine in advanced soft-tissue sarcomas

2024-514827-40-00Phase 2Withdrawn

Sponsor
SELNET
Start
Aug 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised trial of selinexor and Gemmis in leiomyosarcoma (LMS) and malignant peripheral nerve sheath tumor (MPNST), sponsored by SELNET. Primary endpoints: Dose Limiting Toxicities (DLTs) in first cycle (Phase I) and Progression-free survival rate at 6 months (PFSR) (Phase II). Planned start Aug 2024; status: withdrawn.

02

Drugs

selinexorGemmis
03

Conditions

leiomyosarcoma (LMS)malignant peripheral nerve sheath tumor (MPNST)

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