Trial intelligence / Profile preview

Atumelnant open-label long-term extension in congenital adrenal hyperplasia

2024-514846-35-00Phase 2Authorised

Sponsor
Crinetics Pharmaceuticals
Start
Jul 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
16
01

Overview

Phase 2, open-label trial of atumelnant in congenital adrenal hyperplasia (CAH) (2 arms), sponsored by Crinetics Pharmaceuticals. Primary endpoints: Incidence of treatment-emergent adverse events, Incidence of glucocorticoid deficiency, adrenal insufficiency, and adrenal crisis and 2 more. Planned start Jul 2025; status: authorised.

02

Drugs

atumelnant
03

Conditions

congenital adrenal hyperplasia (CAH)

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