Trial intelligence / Profile preview

CC-486 plus venetoclax in previously untreated higher-risk myelodysplastic syndromes

2024-514876-41-00Phase 2Authorised

Sponsor
Groupe Français des Myélodysplasies
Start
Oct 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of azacitidine and venetoclax in myelodysplastic syndrome (MDS), sponsored by Groupe Français des Myélodysplasies. Primary endpoints: Dose-limiting toxicity and Overall response. Planned start Oct 2024; status: authorised.

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Drugs

azacitidinevenetoclax
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Conditions

myelodysplastic syndrome (MDS)

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