Trial intelligence / Profile preview

PELICAN-IPC: pembrolizumab plus neoadjuvant EC-paclitaxel in HER2-negative inflammatory breast cancer

2024-514899-41-00Phase 2Authorised

Sponsor
Institut Paoli-Calmettes
Start
Oct 2024
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of pembrolizumab, cyclophosphamide, epirubicin and paclitaxel in inflammatory breast cancer (IBC) and breast cancer (2 arms), sponsored by Institut Paoli-Calmettes. Primary endpoints: Central pathological complete response rate and Dose-limiting toxicity rate. Planned start Oct 2024; status: authorised.

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Drugs

pembrolizumabcyclophosphamideepirubicinpaclitaxel
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Conditions

inflammatory breast cancer (IBC)breast cancer

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