Trial intelligence / Profile preview

ALICE in high-tumor-burden hepatocellular carcinoma

2024-514912-28-00Phase 3Suspended

Sponsor
Unicancer
Start
Oct 2025
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of durvalumab, tiragolumab, gemcitabine and oxaliplatin in hepatocellular carcinoma (HCC) (2 arms), sponsored by Unicancer. Primary endpoints: Objective response rate and Overall survival. Started Oct 2025; status: suspended.

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Drugs

durvalumabtiragolumabgemcitabineoxaliplatin
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Conditions

hepatocellular carcinoma (HCC)

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