Trial intelligence / Profile preview

First-in-human study of IDRX-42 in metastatic and/or unresectable GIST

2024-514930-19-00Phase 2Authorised

Sponsor
IDRx
Start
Aug 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
10
01

Overview

Phase 2, open-label, single-arm trial of IDRX-42 in gastrointestinal stromal tumor (GIST), sponsored by IDRx. Primary endpoints: Treatment-emergent adverse events and dose-limiting toxicities (Phase 1), Safety in Phase 1b and 2 more. Planned start Aug 2024; status: authorised.

02

Drugs

IDRX-42
03

Conditions

gastrointestinal stromal tumor (GIST)

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