Trial intelligence / Profile preview

PREVENT-iT infection prophylaxis in total joint replacement

2024-515055-38-00Phase 3Authorised

Sponsor
Hamilton Health Sciences
Start
Feb 2025
Modality
Antimicrobial Peptides → Native Peptides → Peptides, Cyclic Peptides → Modified Peptides → Peptides, Small Molecules
Countries
5
01

Overview

Phase 3, randomised trial of vancomycin, chlorhexidine, povidone, benzalkonium chloride and benzyl alcohol in None and periprosthetic joint infection (PJI) (2 arms), sponsored by Hamilton Health Sciences. Primary endpoint: Infection requiring reoperation within 12 months of total joint replacement. Planned start Feb 2025; status: authorised.

02

Drugs

vancomycinchlorhexidinepovidonebenzalkonium chloridebenzyl alcohol
03

Conditions

periprosthetic joint infection (PJI)

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