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Durvalumab + tremelimumab with personalized or standard SIRT versus immunotherapy with on-demand SIRT in non-resectable hepatocellular carcinoma

2024-515127-11-00Phase 2Authorised

Sponsor
LMU Klinikum
Start
Aug 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
2
01

Overview

Phase 2, randomised, open-label trial of durvalumab and tremelimumab in hepatocellular carcinoma (HCC) (3 arms), sponsored by LMU Klinikum. Primary endpoint: Objective response rate. Planned start Aug 2024; status: authorised.

02

Drugs

durvalumabtremelimumab
03

Conditions

hepatocellular carcinoma (HCC)

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