Trial intelligence / Profile preview

Atezolizumab plus WT1 dendritic cell vaccine with platinum/pemetrexed in first-line epithelioid malignant pleural mesothelioma

2024-515293-27-00Phase 2Authorised

Sponsor
Antwerp University Hospital
Start
Nov 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of atezolizumab and WT1 LAMP mRNA dendritic cell vaccine in pleural mesothelioma, sponsored by Antwerp University Hospital. Primary endpoints: Feasibility, Safety - incidence of treatment-related AEs/SAEs and 1 more. Planned start Nov 2024; status: authorised.

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Drugs

atezolizumabWT1 LAMP mRNA dendritic cell vaccine
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Conditions

pleural mesothelioma

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