Trial intelligence / Profile preview

WT1-targeted dendritic cell vaccine as adjuvant immunotherapy for pediatric high-grade glioma and diffuse intrinsic pontine glioma

2024-515295-12-00Phase 2Completed

Sponsor
Antwerp University Hospital
Start
Oct 2021
Modality
Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of WT1 LAMP mRNA dendritic cell vaccine in glioma and diffuse intrinsic pontine glioma (DIPG) (2 arms), sponsored by Antwerp University Hospital. Primary endpoints: Feasibility and Safety. Started Oct 2021; status: completed.

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Drugs

WT1 LAMP mRNA dendritic cell vaccine
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Conditions

gliomadiffuse intrinsic pontine glioma (DIPG)

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