Trial intelligence / Profile preview

VESICANS: Extracellular Vesicles During CAR-T Therapy and ICANS

2024-515328-35-00Phase 4Authorised

Sponsor
CHU Saint-Etienne
Start
Sep 2024
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
1
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Overview

Phase 4, open-label, single-arm trial of lisocabtagene maraleucel, axicabtagene ciloleucel, idecabtagene vicleucel, tisagenlecleucel and brexucabtagene autoleucel in hematopoietic malignancies, lymphoma, leukemia and 2 more, sponsored by CHU Saint-Etienne. Planned start Sep 2024; status: authorised.

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Drugs

lisocabtagene maraleucelaxicabtagene ciloleucelidecabtagene vicleuceltisagenlecleucelbrexucabtagene autoleucel
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Conditions

hematopoietic malignancieslymphomaleukemiamultiple myeloma (MM)immune effector cell-associated neurotoxicity syndrome (ICANS)

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