Trial intelligence / Profile preview

Apixaban or rivaroxaban versus aspirin for primary prevention of thromboembolic complications in JAK2V617F-positive myeloproliferative neoplasms

2024-515362-13-00Phase 3Authorised

Sponsor
Centre Hospitalier Universitaire de Brest
Start
Aug 2024
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised trial of apixaban, rivaroxaban and aspirin in polycythemia vera (PV), thrombocythemia, primary myelofibrosis (PMF) and 1 more (2 arms), sponsored by Centre Hospitalier Universitaire de Brest. Primary endpoint: Time to occurrence of arterial or venous thromboembolic events. Planned start Aug 2024; status: authorised.

02

Drugs

apixabanrivaroxabanaspirin
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Conditions

polycythemia vera (PV)thrombocythemiaprimary myelofibrosis (PMF)Philadelphia-negative myeloproliferative neoplasm

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