Trial intelligence / Profile preview

NESCIO neoadjuvant immuno-oncology in clear cell RCC

2024-515514-40-00Phase 2Authorised

Sponsor
Netherlands Cancer Institute
Start
Aug 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised trial in clear cell renal cell carcinoma (ccRCC) comparing Relatlimab + nivolumab neoadjuvant with Relatlimab + nivolumab + ipilimumab neoadjuvant (2 arms). Primary endpoint: Pathologic response rate. Planned start Aug 2024; status: authorised.

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Drugs

nivolumabrelatlimabipilimumab
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Conditions

clear cell renal cell carcinoma (ccRCC)

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