Trial intelligence / Profile preview

HexAgon-HN: INBRX-106 + Keytruda vs Keytruda in first-line PD-L1-high recurrent/metastatic HNSCC

2024-515538-34-00Phase 3Authorised

Sponsor
Inhibrx Biosciences
Start
Jan 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
13
01

Overview

Phase 3, randomised, double-blind trial in head and neck squamous cell carcinoma (HNSCC) comparing INBRX-106 + Keytruda with Keytruda + placebo (2 arms). Primary endpoints: Objective response rate, Progression-free survival and 1 more. Planned start Jan 2025; status: authorised.

02

Drugs

inbrx-106pembrolizumab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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