Trial intelligence / Profile preview

Phase II study of niraparib plus dostarlimab in PD-L1 positive pleural mesothelioma or non-small cell lung cancer with HRR gene mutations

2024-515555-38-01Phase 2Authorised

Sponsor
University of Turin
Start
Dec 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of dostarlimab and niraparib in pleural mesothelioma and non-small cell lung cancer (NSCLC), sponsored by University of Turin. Primary endpoint: progression free survival. Planned start Dec 2024; status: authorised.

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Drugs

dostarlimabniraparib
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Conditions

pleural mesotheliomanon-small cell lung cancer (NSCLC)

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