Trial intelligence / Profile preview

DO-IT – The DOAC Intravenous Thrombolysis Trial

2024-515561-34-01Phase 4Authorised

Sponsor
Insel Gruppe
Start
Aug 2025
Modality
Recombinant Proteins and Enzymes
Countries
13
01

Overview

Phase 4, randomised trial in ischemic stroke comparing Tenecteplase arm with Alteplase arm (2 arms). Primary endpoint: modified Rankin Scale (mRS) shift at 90 days. Planned start Aug 2025; status: authorised.

02

Drugs

tenecteplasetissue-plasminogen activator
03

Conditions

ischemic stroke

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