Trial intelligence / Profile preview

Cabozantinib plus nivolumab and ipilimumab versus nivolumab and ipilimumab in previously untreated advanced or metastatic intermediate- or poor-risk renal cell carcinoma

2024-515616-47-00Phase 3Authorised

Sponsor
Exelixis, Inc.
Start
Oct 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
23
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Overview

Phase 3, randomised, double-blind trial in renal cell carcinoma (RCC) comparing Cabozantinib + nivolumab + ipilimumab with Placebo + nivolumab + ipilimumab (2 arms). Primary endpoint: Progression-free survival. Planned start Oct 2019; status: authorised.

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Drugs

cabozantinibnivolumabipilimumab
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Conditions

renal cell carcinoma (RCC)

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